Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules

Pronunciation: klor-fen-IHR-ah-meen/sue-do-eh-FED-rin
Generic Name: Chlorpheniramine/Pseudoephedrine
Brand Name: Examples include Dynahist ER and Histade CR

Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules are used for:

Relieving symptoms of sinus congestion, sinus pressure, runny nose, and sneezing due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules are an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, relieving congestion and pressure.

Do NOT use Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules if:

• you are allergic to any ingredient in Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules


• you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems


• you take sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules:

Some medical conditions may interact with Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a fast, slow, or irregular heartbeat


• if you have a history of asthma, lung problems (eg, emphysema), adrenal gland problems (eg, adrenal gland tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your stomach or intestines, ulcers, a blockage of your bladder, trouble urinating, an enlarged prostate, seizures, or an overactive thyroid

Some MEDICINES MAY INTERACT with Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules's side effects


• Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased


• Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules


• Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules:

Use Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules by mouth with or without food.


• Swallow Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules whole. Do not break, crush, or chew before swallowing.


• If you miss a dose of Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules.

Important safety information:

• Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not take diet or appetite control medicines while you are taking Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules without checking with you doctor.


• Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules has pseudoephedrine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.


• If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.


• Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules for a few days before the tests.


• Tell your doctor or dentist that you take Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules before you receive any medical or dental care, emergency care, or surgery.


• Use Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules with caution in the ELDERLY; they may be more sensitive to its effects.


• Caution is advised when using Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules in CHILDREN; they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules while you are pregnant. It is not known if Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules are found in breast milk. Do not breast-feed while taking Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules.

Possible side effects of Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Chlorpheniramine/Pseudoephedrine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules:

Store Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules out of the reach of children and away from pets.

General information:

• If you have any questions about Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.


• Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Chlorpheniramine/Pseudoephedrine Sustained-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Chlorpheniramine/Pseudoephedrine resources

• Chlorpheniramine/Pseudoephedrine Side Effects (in more detail)
• Chlorpheniramine/Pseudoephedrine Use in Pregnancy & Breastfeeding
• Drug Images
• Chlorpheniramine/Pseudoephedrine Drug Interactions
• Chlorpheniramine/Pseudoephedrine Support Group
• 11 Reviews for Chlorpheniramine/Pseudoephedrine - Add your own review/rating

Compare Chlorpheniramine/Pseudoephedrine with other medications

• Hay Fever
• Sinusitis

ratio-Prednisolone

ratio-Prednisolone may be available in the countries listed below.

Ingredient matches for ratio-Prednisolone

Prednisolone

Prednisolone 21-acetate (a derivative of Prednisolone) is reported as an ingredient of ratio-Prednisolone in the following countries:

• Canada

International Drug Name Search

Rhinocort

Generic Name: budesonide nasal (byoo DEH so nide)

Brand Names: Rhinocort Aqua

What is Rhinocort (budesonide nasal)?

Budesonide is a steroid. It prevents the release of substances in the body that cause inflammation.

Budesonide nasal is used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal or year-round allergies. Budesonide is also used to keep nasal polyps from coming back after surgery to remove them.

Budesonide may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Rhinocort (budesonide nasal)?

Before using budesonide, tell your doctor if you have been sick or had an infection of any kind. Also tell your doctor if you have liver disease, glaucoma or cataracts, herpes simplex infection of your eyes, tuberculosis, sores or ulcers in your nose, or if you have recently had injury of or surgery on your nose.

It may take up to 2 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after a week of treatment.

To be sure this medication is not causing harmful effects on your nose or sinuses, your doctor may want to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Budesonide nasal can lower the blood cells that help your body fight infections. Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using budesonide nasal.

Avoid getting this medication in your eyes. If this does happen, rinse with water and call your doctor.

Steroid medicines can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using budesonide nasal.

What should I discuss with my healthcare provider before using Rhinocort (budesonide nasal)?

You should not use this medication if you are allergic to budesonide.

Before using budesonide, tell your doctor if you have been sick or had an infection of any kind. You may not be able to use budesonide nasal until you are well.

Also tell your doctor if you are allergic to any drugs, or if you have:

• 
  

  liver disease;

  
  


• 
  

  glaucoma or cataracts;

  
  


• 
  

  herpes simplex virus of your eyes;

  
  


• 
  

  tuberculosis or any other infection or illness;

  
  


• 
  

  sores or ulcers inside your nose; or

  
  


• 
  

  if you have recently had injury of or surgery on your nose.

  
  

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether budesonide passes into breast milk or if it could harm a nursing baby. Do not use budesonide nasal without telling your doctor if you are breast-feeding a baby.

Steroid medicines can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using budesonide nasal.

How should I use Rhinocort (budesonide nasal)?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

The usual dose of budesonide nasal is 1 to 4 sprays into each nostril once per day. Follow your doctor's instructions.

Before using the spray for the first time, you must prime the spray pump. Shake the medicine well and spray 8 test sprays into the air and away from your face. Spray until a fine mist appears. Prime the spray pump any time you have not used your nasal spray for longer than 2 days. If longer than 2 weeks has passed, rinse the applicator and prime with 2 test sprays.

Shake the medicine bottle well just before each use. It may take up to 2 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after a week of treatment.

To be sure this medication is not causing harmful effects on your nose or sinuses, your doctor may want to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store this medication in an upright position at room temperature, away from moisture and heat.

Throw the medication away after you have used 120 sprays, even if there is still medicine left in the bottle.

What happens if I miss a dose?

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of budesonide nasal is not expected to produce life-threatening symptoms. However, long-term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using Rhinocort (budesonide nasal)?

Avoid getting this medication in your eyes. If this does happen, rinse with water and call your doctor.

Budesonide nasal can lower the blood cells that help your body fight infections. Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using budesonide nasal.

Rhinocort (budesonide nasal) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• 
  

  severe or ongoing nose bleed;

  
  


• 
  

  sores in the nose that won't heal;

  
  


• 
  

  wheezing, trouble breathing;

  
  


• 
  

  vision problems; or

  
  


• 
  

  fever, chills, body aches, flu symptoms.

  
  

Less serious side effects may include:

• 
  

  dry or sore throat, cough;

  
  


• 
  

  irritation in your nose;

  
  


• 
  

  pain, swelling, burning, itching, or irritation in your throat;

  
  


• 
  

  sores or white patches inside or around your nose.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Rhinocort (budesonide nasal)?

Before using budesonide nasal, tell your doctor if you are using any of the following drugs:

• 
  

  HIV /AIDS medicine such as nelfinavir (Viracept) or ritonavir (Norvir);

  
  


• 
  

  an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), troleandomycin (Tao);

  
  


• 
  

  an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);

  
  


• 
  

  an "SSRI" antidepressant such as fluoxetine (Prozac), fluvoxamine (Luvox), or paroxetine (Paxil); or

  
  


• 
  

  a tricyclic antidepressant such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).

  
  

This list is not complete and here may be other drugs that can interact with budesonide nasal. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Rhinocort resources

• Rhinocort Side Effects (in more detail)
• Rhinocort Use in Pregnancy & Breastfeeding
• Rhinocort Drug Interactions
• Rhinocort Support Group
• 0 Reviews for Rhinocort - Add your own review/rating

• Rhinocort Advanced Consumer (Micromedex) - Includes Dosage Information


• Rhinocort Aqua Prescribing Information (FDA)


• Rhinocort Aqua eent Monograph (AHFS DI)


• Rhinocort Aqua Consumer Overview


• Rhinocort Aqua Spray MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Rhinocort with other medications

• Hay Fever

Where can I get more information?

• Your pharmacist can provide more information about budesonide nasal.

See also: Rhinocort side effects (in more detail)

Marcen

Marcen may be available in the countries listed below.

Ingredient matches for Marcen

Ketazolam

Ketazolam is reported as an ingredient of Marcen in the following countries:

• Spain

International Drug Name Search

Arteoptic

Arteoptic may be available in the countries listed below.

Ingredient matches for Arteoptic

Carteolol

Carteolol hydrochloride (a derivative of Carteolol) is reported as an ingredient of Arteoptic in the following countries:

• Belgium


• Czech Republic


• Germany


• Hong Kong


• Luxembourg


• Netherlands


• Poland


• Portugal


• Slovakia


• Spain


• Switzerland


• Taiwan


• Thailand

International Drug Name Search

Lactulose Qualimed

Lactulose Qualimed may be available in the countries listed below.

Ingredient matches for Lactulose Qualimed

Lactulose

Lactulose is reported as an ingredient of Lactulose Qualimed in the following countries:

• France

International Drug Name Search

Topimark

Topimark may be available in the countries listed below.

Ingredient matches for Topimark

Topiramate

Topiramate is reported as an ingredient of Topimark in the following countries:

• Bulgaria

International Drug Name Search